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6 (3) esophageal rupture possibly due to ultrasound probe in a 57-year-old man [;9 (4) diverticular perforation sigmoid and duodenal perforation after ileus tube insertion in a 45 -year-old woman, 13 (5) bowel perforation due to diverticulitis in an individual aged 48 years
Evidence caveat: The combination approach is based on clinical observation and mechanistic reasoning, not controlled trials
The references below summarise the mechanism-of-action and translational rat-model evidence base most relevant to the orthopedic and connective-tissue repair claims discussed in this article
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